Other Services:
Regulatory Dossier Preparation
Expert compilation of registration and licensing dossiers for biocidal and household products, strictly following the formats required by national and international regulatory authorities.
Permitted Daily Exposure (PDE) Reports
Development of PDE dossiers for biocidals and household chemical mixtures to strategically manage and minimalizing cross-contamination risks.
Environmental Risk Assessment Reports
Comprehensive evaluations of the environmental impact and hazard potential of biocidal products, prepared in accordance with EMA and EPA guidelines.
Acute Toxicity Testing
Systemic safety evaluations utilizing alternative methodologies in compliance with OECD TG420, TG423, and TG425 guidelines.
Repeated Dose Toxicity Studies (Subacute/Chronic)
- Subacute & Subchronic Testing: 28-day (OECD TG407) and 90-day (OECD TG408) repeated dose oral toxicity studies to evaluate the safety profiles of chemicals, including biocidal active substances.
- Chronic Toxicity Studies (OECD TG452)
Irritation & Corrosion Testing (Alternative Methods)
- Skin Irritation (OECD TG439)
- Eye Irritation & Serious Eye Damage (OECD TG491, TG492)
- Skin Corrosion (OECD TG431)
- Corneal Opacity & Permeability (OECD TG437)
Genotoxicity & Mutagenicity Assays
- Ames Test (OECD TG471): Bacterial reverse mutation assay used to evaluate the mutagenic potential of chemical compounds.
- HPRT Assay (OECD TG476): Mammalian cell gene mutation test targeting the HPRT gene to identify mutagenic agents.
- Comet Assay (OECD TG489): In vivo mammalian alkaline assay for the quantitative measurement of DNA strand breaks.
- DNA Damage Analysis: Spectrophotometric measurement of DNA single and double-strand breaks.
Elemental & Heavy Metal Analysis
High-sensitivity detection and quantification of heavy metals and elemental profiles in biocidal products utilizing ICP-MS or AAS instrumentation.